美高梅赌场八周年-美高梅赌场h

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周建業
作者:周建業    編輯:吳賽     校審: 杜國云 郭力 審簽: 郭力      發布時間:2024-01-23    訪問量:

周建業,漢族,19786月出生。博士,教授,碩士生導師。國家民委青年英才,中國非公立醫療機構協會口腔預防專委會主委,中國非公立醫療機構協會研發中心常務副主任,甘肅生物工程學會科普與教育專委會主委。主持并以主要完成人參與國家自然科學基金5項,主持并以主要完成人參與省部級項目20多項,主持橫向基金3項;發表論文80余篇;獲得省級科技創新創業二等獎1項,獲地級進步一等獎1,為團隊成員,獲得國家科技創新團隊獎1項;獲得發明專利6項,實用新型專利3。近年來,注重基礎研究與產業轉化的結合。在口腔核磁,等離子刀,口腔護理產品等方面帶隊做出重要成果,并使相關企業達到3億以上產值。

課題:

1、甘肅特有少數民族兒童口腔微生物群體感應與齲病的相互關系研究,20181-202112月,2017國家自然科學基金地區基金項目(31560159),3/1045萬。

2、甘肅省科技廳:一種新型頜骨骨支架材料的開發,20YF3GA020,20211-202212月,25萬。

3、基于3D打印的數字化口腔醫療器械研發及應用研究,梅108號;20208-20228月,300萬(橫向項目)。

4、冰核細菌在中草藥綠色種植病蟲害防治中的應用,FXH2020002;20206-20216月;30萬(橫向項目)。

5、篩選及培養高通量藥物篩選平臺的建立,LTY202000820206-20216月;100萬(橫向項目)。

6、保安族牙周炎中免疫與微生物群落結構研究,20171-201912月,2017西北民族大學中央高校重點培育項目(31920170162),1/9,13萬。

7甘肅臨夏回族自治州學齡兒童齲病微生物群落結構及其影響機理研究,20151-201912月,2015國家自然科學基金地區基金項目(31560159),1/1045萬。

8、Apidaecin抗菌肽在畢赤酵母高效分泌表達的反應器開發與研究,20115-201312月,2011年甘肅省科技支撐計劃項目,1/65萬。

9、口腔微生物與口腔常見疾病的關系研究,20181-202112月,2017甘肅省創新群體研究項目(17JR5RA274),3/1050萬。

10、舌鱗狀細胞癌患者口腔微生物群落結構多樣性的研究,20169-20188月,2016甘肅省省青年科技基金計劃項目(1606RJYA238),2/10,2萬。

11 甘肅特有少數民族齲病相關微生物的生態遺傳特征研,20141-201712月,2014國家自然科學基金地區基金項目(31360124),3/1051萬。

12、齲病、牙周炎微生物拮抗機理及預防試劑研發(20141-201612月),2013年甘肅省科技廳國際合作項目,2/10,20萬。

13甘肅省特有少數民族口腔微生物群落結構與牙周炎發病的關系研究,20141-201712月,2012國家自然科學基金地區基金項目(31160124),3/10,56萬。

14、甘肅省特有少數民族齲病分子流行病學研究(20111-201312),2010甘肅省科技廳國際合作項目(1011WCGA168),2/10,10萬。

15、EGFP轉染牙齦卟啉單胞菌及其在種植體周圍炎中的定植研究,20131-201512月,2012年度甘肅省自然科學基金計劃項目(1208RJZA201),2/10,3萬元。

16、甘肅特有少數民族兒童口腔微生物群體感應與齲病的相互關系研究項目,批準號:31760159/ C0309國家自然科學基金委,45萬,2/10, 年限:2018.01-2021.12

172019扶貧助弱 健康口腔——甘肅臨夏州少數民族全生命周期口腔健康扶貧示范項目,經費49.9萬元,中國牙病防治基金會

18、口腔微生物與口腔常見疾病的關系研究   項目批準號:17JR5RA274,甘肅省科技廳基礎研究創新群體,50萬,年限:2017.01-202109,2/12

19、20202022年校級生物材料創新團隊,60

20、20239月甘肅省科技計劃項目高原地區急性心肌梗死患者口腔菌群和腸道菌群特征分析”3


主要論文:

(1) Guoyun Ma, Liya,Ma, Zhou J*, et al. Comparison of oral microbial community structure among the same ethnic group in different living environments[J]. BioMed Research International.2022:4(5)

(2) Ikram Khan, Imran Khan3,... Zhou J, et al. Comparison of Microbial Populations in the Blood of Patients With Myocardial Infarction and Healthy Individuals.Frontiers in Microbiology,2022:

(3) Ikram Khan, Imran Khan3,... Zhou J, et al. Analysis of the blood bacterial composition of patients with acute  coronary syndrome and chronic coronary syndrome. Frontiers in cellutar and infection microbiology.

(4) Khan I, Khan I, Jianye Z, et al. Exploring blood microbial communities and their influence on human cardiovascular disease[J]. Journal of Clinical Labora- tory Analysis, 2022: e24354.(1)

(5) Khan I, Khan I, Jianye Z, et al.Analysis of mitochndrial DNA mutation in pakistani women gestations diabetes melltitus. Intenational journal of biomedicine

(6) Wu S, Yu F, Zhou J*, et al. Do Maternal Microbes Shape Newborn Oral Microbes?[J]. Indian Journal of Microbiology, 2020.

(7)Xiao Ma, Xuefei Zhang, Jia Liu.,Zhou J. The correlations between Th1 and Th2 cytokines in human alveolar echinococcosis, BMC Infectious Diseases 2020,doi: 10.21203/rs.2.21197/v1 (2)

(8) Li Y , Gao X , Zhou J. et al. Modification of Mcl-1 alternative splicing induces apoptosis and suppresses tumor proliferation in gastric cancer[J]. (2020) Aging, 12(19):19293-19315.a

(9) Zhou J, Jiang N, Wang Z, Li L, Jumei Zhang, Ma R, Nie H , Li Z. Influences of pH and iron on the salivary microbiome in individuals with and without caries.[J]. Applied and environmental microbiology, 2017, 83(4): e02412-16.

(10) Zhou J, Yao Y, Jiao K, Zhang J, Zheng X, Wu F, Hu X, Li J, Yu Z, Zhang G, Jiang N, Li Z. Relationship between Gingival Crevicular Fluid Microbiota and Cytokine Profile in Periodontal Host Homeostasis[J]. Frontiers in Microbiology, 2017, 8:2144.

(11) Yao Y, Wei Y, Wei L, Zhou J*. Effect of Inoculum on Anaerobic Co-digestion of Vegetable Processing Wastes and Cattle Manure at High Solids Concentration[J]. Waste& Biomass Valorization, 2017(6):1-8. (9)

(12) Zhou J, Jiang N, Wang S, Hu X, Jiao K, He X, Li Z, Wang J.. Exploration of Human Salivary Microbiomes—Insights into the Novel Characteristics of Microbial Community Structure in Caries and Caries-Free Subjects[J]. PloS one, 2016, 11(1): e0147039.

(13) Zhou J, Zhu Y, Yu Z, Jiao K, Wu F, Li Z. Microbial community structure in saliva from children of the Baoan nationality with or without dental caries in gansu, China[J]. Biomedical Research, 2017, 28(1): 306-308.

(14) Yao Y, Zhou J*,An L, Kafle G K, et al. Role of soil in improving process performance and methane yield of anaerobic digestion with corn straw as substrate[J]. Energy, 2018, 151

(15) Zhou J, Jiang N, Jiao K, Yu Z, Zheng X, Zhang J, Wu F, Li J, Li Z. Bacterial community of saliva in adults with and without periodontitis[J]. International journal of clinical and experimental medicine,2016, 9(8): 16192-16198.

(16) Huang H,Chen L, Zhang X, Wu S, Yi G, Li Z, Zhou J#. "Untargeted metabolomics analysis for a strain of Bacillus subtilis isolated from the oral cavity." INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 11.4 (2018): 3729-+.

(17) Hu X, Li Z, Zhou J, Yu Z, Zhang J, Guo M. Analysis of the association between polymorphisms in the vitamin D receptor (VDR) gene and dental caries in a Chinese population[J]. Genet Mol Res, 2015, 14(3): 11631-11638.

(18) Li Z, Hu X, Zhou J, Li Z, Hu X, Zhou J, Xie X, Zhang J. Genetic polymorphisms in the carbonic anhydrase VI gene and dental caries susceptibility[J]. Genet Mol Res, 2015, 14(4): 5986-5993.

(19) Tingli Zhang,Yonghong Li, Zhou J. et al. "Comparison of the community-acquired

pneumonia and COVID-19 at the early stage: Findings from two cohort studies”Annals of Palliative Medicine, (2021)21-2006,

(20) Xiao-Pan Hu1, Tian-Zhu Song1, Yan-YanZhu1,Zhou J. et al.Associationof ENAM, TUFT1,MMP13, IL1B, IL10 and IL1RNgene polymorphism anddental cariessusceptibilityin Chinese children   Journal of InternationalMedical Research  2019, Vol. 47(4) 1696–1704

(21)Lingli Wu, Zhiqiang Li, Zhou J. et An association analysis for genetic factors for dental caries susceptibility in a cohort of Chinese children[J]. Oral Diseases, 2020.

(22) Khan I, Khan I, . Zhou J. et Circulating microbiota and metabolites: Insights into cardiovascular diseases J Clin Lab Anal. 2022;00:e24779.

(23) Tingli Zhang,Yonghong Li, Zhou J. et al. "Comparison of the community-acquired

pneumonia and COVID-19 at the early stage: Findings from two cohort studies”Annals of Palliative Medicine, (2021)21-2006

(23)Fangchen, Liu;Rui, Ma; Zhou J. et al. The Influence of Different Pore Sizes of Bovine Bone Scaffold Material on the Oral Microbiota. Journal of Biomaterials and Tissue Engineering. 2023.05

(24)Cheng, XRui, Ma; Zhou J. et al.Preparation and osteogenic properties of β-TCP+HA+GO Composites. Journal of Biomaterials and Tissue Engineering. 2023.06

(25)Ikram Khan, Gao Jianli, Mian Gul Hilal, Lei Shengnan, Imran Khan, Naqash Alam, Zhou Jianye, Li Zhiqiang, and An Lizhe. (2022). Glucose: an ongoing risk factor for myocardial infarction. Cardiology research and cardiovascular medicine. www.doi.org.10.29011/2575-7083-100183.

(26) Ikram Khan, Anum A, Khan I, Khan M, Ali F, Khan S, Khan F, Zhou Jianye, Lizhe A, Zhiqiang L. (2022). Analysis of Mitochondrial DNA Mutation in Pakistani Women with Gestational Diabetes Mellitus. International Journal of Biomedicine. doi.org/10.21103/Article12(3)_OA17.

(27) Xiao-Pan Hu1, Tian-Zhu Song1, Yan-YanZhu1,Zhou J. et al.Associationof ENAM, TUFT1,MMP13, IL1B, IL10 and IL1RNgene polymorphism anddental cariessusceptibilityin Chinese children   Journal of InternationalMedical Research  2019, Vol. 47(4) 1696–1704

(28)Lingli Wu, Zhiqiang Li, Zhou J. et An association analysis for genetic factors for dental caries susceptibility in a cohort of Chinese children[J]. Oral Diseases, 2020.


授權專利

1. 具有減振防旋功能的牙科種植體, 2015.10.28,中國,201220375036.4,周建業,陳宏偉,王記增,周又和,李志杰,范勤,劉斌。

2. 一種酸激活CSP靶向抗菌肽及其制備和應用,2015.07.29, 中國,01210314814.3,周建業,張偉,王記增,林志偉,陳熙明,李志杰。

3. 偏心軸式半固定阻鼾器,2015.10.28,中國,ZL201310169423.1,周建業, 李志強,胡曉潘,張軒,焦康禮,王記增。

4. 一種骨支架復合材料的制備方法;發明專利;專利號:ZL201710512368.X

5. 實用新型專利:專利名稱:一種采樣拭子取樣頭及新型人體采樣硅膠拭子;專利號:202020413456.X

6. 2022/02/18 白仲添,張保新,席莉莉,周建業, 國家發明專利, PCID2蛋白在制備或篩選抗腫瘤藥物中的應用及具有抗腫瘤活性的化合物(ZL2021 1 0364129.0). 申請日期: 2021/4/3

7. Zhou, Jianye; Jiao, Kangli; Zhang, Xuan; Song, Tianzhu; Zhang, Jumei; Zheng, Xin; Hu, Xiaopan; Li, Zhiqiang and Xie, Xiaodong A Preparation Method of Bone Scaffold Composite Material Patent number: 2021103980


獲得學術獎勵


1. 周建業,(2/13),甘肅省特有少數民族齲病的分子流行病學研究,甘肅省教育廳,甘肅省高等學??茖W研究優秀成果獎自然科學獎,一等獎(批準號:2015KJ-207),2015.

2. 地級科技進步獎1項:周建業,(1/2),青海省海西州科技創新獎;三等獎;獲獎名稱:一種新型頜骨骨支架材料的研究與制備,2021.

3. 馬忠仁、柏家林、馮若飛、周建業等,國家科技創新團隊獎,2021.


4. 周建業等,甘肅省科技廳創新創業獎,二等獎,青少年心理健康預警機器人研發. 2022


著作

1、周建業 林永盛 實用口腔健康管理,中國科學技術出版社,2023.9

2、周建業  頜骨修復中復合材料的應用,中國科學技術出版社,2023.9



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